Research
Coronavirus
In Hong Kong, Prince of Wales Hospital was one of the heavy battle fields of SARS in 2003. As the teaching hospital of The Chinese University of Hong Kong, faculty and staff members of the university were actively involved in managing the outbreak. In 2012, MERS-CoV, a related coronavirus was reported to cause life-threatening infections in the Middle East. In late 2019, a new coronavirus (SARS-CoV-2) emerged. In three years, above 772 million confirmed COVID-19 cases and 6.9 million deaths from over 200 countries and places were reported to the World Health Organization.
Clinical research
- Exhaled air dispersion during application of various forms of respiratory therapy in the clinical setting
- Clinical characteristics, pathogenesis of and immunological response to SARS-CoV infection
- Safety profile and clinical and virological outcomes of COVID-19 treatment
- Trajectory of SARS-CoV-2 neutralising antibody response in convalescent COVID-19 patients
- Assessment of the COVID-19 vaccine performance and determination of the associated biomarkers
- Local mucosal antibody and systemic antibody responses upon infection and vaccination
- Evaluation of the immune responses in hybrid immunity and mixed vaccine strategies
Laboratory research
- Application of molecular, genomic and proteomic techniques to detect and monitor viral and bacterial infections
- Pathogenesis of zoonotic coronaviruses
- Development of novel treatment options at pre-clinical stage
- Metagenomic study on respiratory virus profile
- Humoral response to COVID-19 vaccines in people living with HIV and general population
- Laboratory diagnosis of SARS-CoV-2
- Host innate immune responses against SARS-CoV-2 infection of primary nasal epithelial cells at different age groups
Public health research
- Epidemiology of MERS in South Korea
- Using big data to assess the effect of exposure settings in COVID-19 outbreaks
- Community-based surveillance for SARS-CoV-2 infection
- Public health policies for epidemic control